IUAP - P7/10

Molecular and Cellular Mechanisms of Electrical Excitability in the Heart and Central Nervous System


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At the annual scientific meetings work progress is presented and discussed with keynote lectures highlighting state-of-the art. These meetings are open.


The second annual meeting will be organized on Tuesday 7th of October, at the "Leuven Institute for Ireland" (Janseniusstraat 1, 3000 Leuven). You can register for the meeting by sending a mail to ilse.lenaerts@med.kuleuven.be.



9h – 10h: Registration & coffee


10h – 12h: WP’s presentation & work in progress


10:00 – 10:10 The IAP program: Introduction — Karin Sipido


10:10 – 10:35 WP1: Molecular architecture of ion channels, macrocomplexes

and multi-channel interactions — Steve Peigneur

Work in progress: Steve Peigneur: “Venom peptides as potent ion channel modulators.”

10:35 – 11:00 WP2: Mechanisms of normal and abnormal pacemaking —

Vincent Seutin

Work in progress: Fabian Philippart: “Quantification of somatic calcium currents in midbrain dopaminergic neurons”.


11:00 – 11:15 Pause


11:15 – 11:40 WP3: Linking Ca2+ homeostasis and electrical excitability —

Luc Leybaert

Work in progress: Nan Wang: “Remodeling of Cx43 hemichannels in ventricular myocardium in hearts exposed to chronic ischemia.”

11:40 – 12:05 WP4: Ligand-gated ion channels in plasticity of excitability —

Serge Schiffmann

Work in progress: Laurie Lambot: “Role of NMDA-R in striatopallidal neurons.”

12:05 – 12:30 WP5: Integrative approaches and translational studies exploring novel strategies targeting ion channels in disease — Karin Sipido

Work in progress: Peter Haemers: “Atrial remodeling in AF progression. Insights from AF sheep model.”


12h30 – 14h30: Lunch and posters (16 poster presentations)


14h30 – 16h: Keynote lectures


14:30 – 15:15Prof. Charpentier: “SCN5A-related fibrotic remodeling and dilated cardiomyopathy.”

15:15 – 16:00Dr. Vriens: “A thermoTRP with multiple ion permeation pathways.”